Everyone feels tired now and then. A late night, a stressful week, a poor night’s sleep, or an especially busy season of life can leave anyone dragging. But there is a difference between occasional tiredness and the kind of fatigue that settles in, lingers, and begins to interfere with your ability to enjoy life.

If you wake up tired, depend on caffeine to get through the day, hit a wall in the afternoon, or feel like ordinary tasks require extraordinary effort, your body may be trying to tell you something. Fatigue is not a disease by itself. It is a symptom. And because it can have so many possible causes, it is often one of the most frustrating symptoms to sort out

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